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McCulkin case summary continues

The judge in the murder trial of Vincent O'Dempsey will continue instructing the jury on how it can reach its verdict for a second day.

O'Dempsey, 78, has pleaded not guilty to the murders of Barbara McCulkin and her two daughters - Vicki, 13, and Leanne, 11 - who were last seen at their Highgate Hill home on the night of January 16, 1974.

A three-week trial in the Brisbane Supreme Court has heard from more than 50 witnesses, including three people who claimed O'Dempsey confessed his involvement in the murders.

The jury is expected to begin considering its verdict as early as Thursday once Justice Peter Applegarth finishes his final summations.